Genetic Screening Basics

Put simply, genetic screening allows you to discover whether you or your partner carry a genetic disease that you might pass on to your child. It doesn't matter who you are or what your family history is, there's a one in two chance that you carry a genetically inherited disease that our Super Panel screens for. Screening can also reveal chromosomal disorders that may affect the health of your child.

Genetic Screening Basics

What is Genetic Screening?

Genetic screening is a way to look at your genes and detect if you are a carrier of an inherited genetic disease — such as cystic fibrosis — that you might pass on to your children. Other screens allow you to look for non-inheritable genetic conditions that can lead to conditions like Down syndrome.

When Should I Be Screened?

The ideal time to undergo carrier screening is prior to pregnancy. By doing so, you can get information to help you plan your reproductive journey. However, even couples who are expecting can benefit from what screening can reveal.

Everyone — regardless of health, family history, age, or ancestry — can benefit from undergoing genetic screening. Without screening, it's impossible to know whether you or your partner are carriers of an inheritable genetic condition that you can pass on to your children.

Learn More
When Should I Be Screened?

What Does Clarity Genetics Screen For?

We screen for 120 different inheritable diseases and non-inherited genetic conditions that can affect your pregnancy, the health of your baby, and your family's future. You can learn more about our various screens — and which sets of screens (or "panels") align with where you are in your reproductive journey.

Discovering Your Genetic Inheritance

Every cell in our body carries two sets of genes — a set from each parent (one from the mother's egg and one from the father's sperm). Genes are made up of chromosomes, which are made up of DNA. And by looking at your DNA, screening can reveal your risk for carrying and passing along a gene or a chromosomal abnormality to your child. Genes can be either "recessive" or "dominant." The charts below show the possible outcomes depending on the genes of the mother's egg and those from the father's sperm.

Recessive Genetic Disease

A recessive genetic disease occurs when both copies of a particular gene have pathogenic variants. If you have one copy of a gene with a variant and one normal copy of that same gene, you are considered a "carrier" for that recessive genetic disease even though you are not affected by that disease.

In order for carriers to pass on a recessive gene, both partners would have to be carriers of the same genetic disease.

Dominant Genetic Disease

A dominant genetic disease occurs when one of the two copies of a particular gene has a pathogenic variant. Only one of the copies of the gene needs to have a pathogenic variant in order for an individual to be affected by a dominant genetic disease (recessive diseases require both copies to have variants). If either you or your partner have a dominant genetic disease, you run a 50% risk of having a child affected by that genetic disease.

X-Linked Disorders

The X and Y chromosomes (often called the sex chromosomes) determine whether a baby is male or female. Males have one X and one Y, while females have two X chromosomes. Some disorders are caused by variants or alterations of the X chromosome. Generally, if a woman has a pathogenic variant on one of the genes located on an X chromosome, she is considered a carrier — and has a 50% chance of passing that variant onto her children. If she passes on the variant on to a male child, that child can be affected with the condition. Affected males will not pass the variant onto their sons, but daughters of affected males will be carriers of the variant. Female carriers rarely develop symptoms of the condition but their daughters have a 50% chance of being carriers.

Talk to a Genetic Counselor

As a Clarity client, you'll have access to personal genetic counselors who can help explain the results of your screens and provide insight on how to move forward. To schedule a personal conference to discuss your screen results, click the link below or call(866) 661-7966​

Discuss Your Screening Results